A non-electrostatic spacer for aerosol delivery.

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A non-electrostatic spacer for aerosol delivery.

A pear shaped non-electrostatic spacer, composed of steel with a volume of 250 ml and equipped with a facemask containing integrated inlet and outlet valves for inspiration and expiration, was compared with three plastic spacers. The plastic spacers were primed with repeated puffs from a budesonide pressurised metered dose inhaler (p-MDI) to minimise the electrostatic charge on the plastic. The...

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Electrostatic charge on a plastic spacer device influences the delivery of salbutamol.

The aim of this study was to determine whether electrostatic charge on a plastic spacer decreases the delivery of salbutamol from a pressurized metered-dose inhaler (pMDI) and, if so, to find an optimal and practical treatment to remove the charge. Ten single actuations from a salbutamol pMDI were drawn through different Volumatic spacers at a constant flow of 60 L.min-1. The efficacies of diff...

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Variability of aerosol delivery via spacer devices in young asthmatic children in daily life.

Pressurized metered dose inhalers (pMDI) are widely used together with spacers for the treatment of asthma in children. However, the variability of daily medication dose for pMDI/spacer combinations is not known. Electrostatic charge is a potential source of dose variability. Metal spacers have no static charge. This study assessed and compared within-subject variability of aerosol delivery of ...

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Aerosol Drug Delivery for Infants

INTRODUCTION Every year, approximately 2,500 children are admitted to the pediatric intensive care unit (PICU) at the Children’s Hospital of Pittsburgh at the University of Pittsburgh Medical Center alone [1]. Respiratory illnesses are one of the leading causes of admission [1]. For children with acute respiratory illnesses, inhaled medications are a common method of treatment, as this allows p...

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oPtimal aerosol delivery

Equivalent clinical results can be achieved from any delivery device, providing the patient can use it correctly. Selection of the appropriate device for each patient requires consideration of multiple factors. Inhaler technique should be demonstrated by the patient at each visit, assessed by the health-care provider, and where necessary, training to optimise aerosol delivery should be repeated...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1995

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.73.3.226